Kristin Hedgepath Gilchrist
Doctoral Alumnus

 

Kristin Gilchrist

 

EDUCATION: 

  • BS Biomedical Engineering / Electrical Engineering, Vanderbilt University, 1997 
  • MS Electrical Engineering, Stanford University, 1999
  • PhD Electrical Engineering, Stanford University, 2003

WORK EXPERIENCE:

  • 2003-present: Research Scientist at MCNC Research & Development Institute
  • 1998-2003: Research Assistant at Stanford University
  • Summer 1997: Counselor at South Carolina Academic Governor's School
  • Summer 1996: Research Assistant at Medical University of South Carolina  

RESEARCH INTERESTS: My PhD research focused on hardware development and data analysis techniques for cell-based biosensors which utilize electrically active cells cultured on extracellular microelectrode arrays to detect physiologically active compounds.  In my current position at MCNC, I am developing a variety of microfabricated chemical and biological sensors. 

PUBLICATIONS:  

 

K. H. Gilchrist, L. Giovangrandi, R. H. Whittington, and G. T. A. Kovacs, "Sensitivity of cell-based biosensors to environmental variables," Biosensors & Bioelectronics, vol. 20, pp. 1397-1406, 2005.

R.H. Whittington, K.H. Gilchrist, L. Giovangrandi, and G.T.A. Kovacs, “A multi-parameter, feedback-based electrical stimulation system for cardiomyocyte cultures.” Proc. 12th Int. Conf. on Solid-State Sensors, Actuators, and Microsystems (Boston, MA, June 8-12, 2003).

N.J. Mourlas, K.H. Gilchrist, L. Giovangrandi, N.I. Maluf, and G.T.A. Kovacs, “An in-line osmometer for application to a cell-based biosensor system,” Sensors and Actuators B (Chemical), vol. B83, no. 1-3, pp. 41-47, 2002.

K.H. Gilchrist, V.N. Barker, L.E. Fletcher, B.D. DeBusschere, P. Ghanouni, L. Giovangrandi, and G.T.A. Kovacs, "General purpose, field-portable cell-based biosensor platform," Biosensors and Bioelectronics, vol. 16, no. 7-8, pp. 557-564, 2001.

A.M. Aravanis, B.D. DeBusschere, A.J. Chruscinski, K.H. Gilchrist, B.K. Kobilka, and G.T.A. Kovacs, "A genetically engineered cell-based biosensor for functional classification of agents," Biosensors and Bioelectronics, vol. 16, no. 7-8, pp. 557-564, 2001.

K.H. Gilchrist, L. Giovangrandi, and G.T.A. Kovacs, "Analysis of microelectrode-recorded signals from a cardiac cell line as a tool for pharmaceutical screening," in Proc. 11th Int. Conf. on Solid-State Sensors and Actuators (Munich, Germany, June 10-14, 2001, pp.390-393).

K.R. Hedgepath, R. Mukherjee, Z. Wang, and F.G. Spinale, "The relation between changes in myocyte orientation and contractile function with electrical field stimulation," Basic Research in Cardiology, vol. 92, no. 6, pp. 385-390.

 

CONTACT INFORMATION:

MCNC Research & Development Institute
P.O. Box 13910
3021 Cornwallis Rd.

Research Triangle Park, NC 27709

kgilchrist_at_rti.org